📄 论文总结
通用基础模型在医疗运营决策中的临床适用性不足 / Generalist Foundation Models Are Not Clinical Enough for Hospital Operations
1️⃣ 一句话总结
这项研究开发了基于医疗记录预训练的专业模型Lang1,在真实医疗运营任务中显著优于通用大模型,证明医疗AI系统需要结合领域预训练、监督微调和现实评估才能有效支持医院决策。
Hospitals and healthcare systems rely on operational decisions that determine patient flow, cost, and quality of care. Despite strong performance on medical knowledge and conversational benchmarks, foundation models trained on general text may lack the specialized knowledge required for these operational decisions. We introduce Lang1, a family of models (100M-7B parameters) pretrained on a specialized corpus blending 80B clinical tokens from NYU Langone Health's EHRs and 627B tokens from the internet. To rigorously evaluate Lang1 in real-world settings, we developed the REalistic Medical Evaluation (ReMedE), a benchmark derived from 668,331 EHR notes that evaluates five critical tasks: 30-day readmission prediction, 30-day mortality prediction, length of stay, comorbidity coding, and predicting insurance claims denial. In zero-shot settings, both general-purpose and specialized models underperform on four of five tasks (36.6%-71.7% AUROC), with mortality prediction being an exception. After finetuning, Lang1-1B outperforms finetuned generalist models up to 70x larger and zero-shot models up to 671x larger, improving AUROC by 3.64%-6.75% and 1.66%-23.66% respectively. We also observed cross-task scaling with joint finetuning on multiple tasks leading to improvement on other tasks. Lang1-1B effectively transfers to out-of-distribution settings, including other clinical tasks and an external health system. Our findings suggest that predictive capabilities for hospital operations require explicit supervised finetuning, and that this finetuning process is made more efficient by in-domain pretraining on EHR. Our findings support the emerging view that specialized LLMs can compete with generalist models in specialized tasks, and show that effective healthcare systems AI requires the combination of in-domain pretraining, supervised finetuning, and real-world evaluation beyond proxy benchmarks.
通用基础模型在医疗运营决策中的临床适用性不足 / Generalist Foundation Models Are Not Clinical Enough for Hospital Operations
这项研究开发了基于医疗记录预训练的专业模型Lang1,在真实医疗运营任务中显著优于通用大模型,证明医疗AI系统需要结合领域预训练、监督微调和现实评估才能有效支持医院决策。