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arXiv 提交日期: 2026-02-03
📄 Abstract - SLIM-Diff: Shared Latent Image-Mask Diffusion with Lp loss for Data-Scarce Epilepsy FLAIR MRI

Focal cortical dysplasia (FCD) lesions in epilepsy FLAIR MRI are subtle and scarce, making joint image--mask generative modeling prone to instability and memorization. We propose SLIM-Diff, a compact joint diffusion model whose main contributions are (i) a single shared-bottleneck U-Net that enforces tight coupling between anatomy and lesion geometry from a 2-channel image+mask representation, and (ii) loss-geometry tuning via a tunable $L_p$ objective. As an internal baseline, we include the canonical DDPM-style objective ($\epsilon$-prediction with $L_2$ loss) and isolate the effect of prediction parameterization and $L_p$ geometry under a matched setup. Experiments show that $x_0$-prediction is consistently the strongest choice for joint synthesis, and that fractional sub-quadratic penalties ($L_{1.5}$) improve image fidelity while $L_2$ better preserves lesion mask morphology. Our code and model weights are available in this https URL

顶级标签: medical computer vision model training
详细标签: diffusion models medical imaging mri synthesis lesion segmentation lp loss 或 搜索:

SLIM-Diff:一种用于数据稀缺的癫痫FLAIR MRI的、采用Lp损失的共享潜在图像-掩码扩散模型 / SLIM-Diff: Shared Latent Image-Mask Diffusion with Lp loss for Data-Scarce Epilepsy FLAIR MRI


1️⃣ 一句话总结

本文提出了一种名为SLIM-Diff的新型紧凑扩散模型,它通过一个共享的神经网络架构和可调节的Lp损失函数,有效解决了在数据稀缺的癫痫FLAIR MRI图像中,同时生成高质量脑部解剖图像和精细病灶分割图的难题。

源自 arXiv: 2602.03372