EHRWorld:一个面向患者的、用于长周期临床轨迹的医学世界模型 / EHRWorld: A Patient-Centric Medical World Model for Long-Horizon Clinical Trajectories
1️⃣ 一句话总结
这篇论文提出了一个名为EHRWorld的新型医学世界模型,它通过基于真实电子健康记录的大规模时序数据进行因果训练,有效解决了现有大语言模型在模拟长期疾病发展和治疗结果时状态不一致、误差累积的问题,实现了更稳定、准确和高效的临床模拟。
World models offer a principled framework for simulating future states under interventions, but realizing such models in complex, high-stakes domains like medicine remains challenging. Recent large language models (LLMs) have achieved strong performance on static medical reasoning tasks, raising the question of whether they can function as dynamic medical world models capable of simulating disease progression and treatment outcomes over time. In this work, we show that LLMs only incorporating medical knowledge struggle to maintain consistent patient states under sequential interventions, leading to error accumulation in long-horizon clinical simulation. To address this limitation, we introduce EHRWorld, a patient-centric medical world model trained under a causal sequential paradigm, together with EHRWorld-110K, a large-scale longitudinal clinical dataset derived from real-world electronic health records. Extensive evaluations demonstrate that EHRWorld significantly outperforms naive LLM-based baselines, achieving more stable long-horizon simulation, improved modeling of clinically sensitive events, and favorable reasoning efficiency, highlighting the necessity of training on causally grounded, temporally evolving clinical data for reliable and robust medical world modeling.
EHRWorld:一个面向患者的、用于长周期临床轨迹的医学世界模型 / EHRWorld: A Patient-Centric Medical World Model for Long-Horizon Clinical Trajectories
这篇论文提出了一个名为EHRWorld的新型医学世界模型,它通过基于真实电子健康记录的大规模时序数据进行因果训练,有效解决了现有大语言模型在模拟长期疾病发展和治疗结果时状态不一致、误差累积的问题,实现了更稳定、准确和高效的临床模拟。
源自 arXiv: 2602.03569