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arXiv 提交日期: 2026-03-18
📄 Abstract - DeepCORO-CLIP: A Multi-View Foundation Model for Comprehensive Coronary Angiography Video-Text Analysis and External Validation

Coronary angiography is the reference standard for evaluating coronary artery disease, yet visual interpretation remains variable between readers. Existing artificial intelligence methods typically analyze single frames or projections and focus mainly on stenosis, limiting comprehensive coronary assessment. We present DeepCORO-CLIP, a multi-view foundation model trained with video-text contrastive learning on 203,808 angiography videos from 28,117 patients across 32,473 studies at the Montreal Heart Institute and externally validated on 4,249 studies from the University of California, San Francisco. DeepCORO-CLIP integrates multiple projections with attention-based pooling for study-level assessment across diagnostic, prognostic, and disease progression tasks. For significant stenosis detection, the model achieved an AUROC of 0.888 internally and 0.89 on external validation. Mean absolute error against core laboratory quantitative coronary angiography was 13.6%, lower than clinical reports at 19.0%. The model also performed strongly for chronic total occlusion, intracoronary thrombus, and coronary calcification detection. Transfer learning enabled prediction of one-year major adverse cardiovascular events with AUROC 0.79 and estimation of left ventricular ejection fraction with mean absolute error 7.3%. Embeddings also captured disease progression across serial examinations. With a mean inference time of 4.2 seconds in hospital deployment, DeepCORO-CLIP provides a foundation for automated coronary angiography interpretation at the point of care. Code, sample data, model weights, and deployment infrastructure are publicly released.

顶级标签: medical computer vision multi-modal
详细标签: medical imaging coronary angiography video-text analysis foundation model clinical validation 或 搜索:

DeepCORO-CLIP:一个用于全面冠状动脉造影视频-文本分析及外部验证的多视角基础模型 / DeepCORO-CLIP: A Multi-View Foundation Model for Comprehensive Coronary Angiography Video-Text Analysis and External Validation


1️⃣ 一句话总结

本研究开发了一个名为DeepCORO-CLIP的人工智能基础模型,它能够像专家一样,通过分析多角度的冠状动脉造影视频,不仅准确识别血管狭窄等病变,还能预测患者未来一年的心血管事件风险,并在两家不同医院的真实数据中验证了其有效性和快速诊断能力。

源自 arXiv: 2603.17675