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arXiv 提交日期: 2026-03-25
📄 Abstract - 3D-LLDM: Label-Guided 3D Latent Diffusion Model for Improving High-Resolution Synthetic MR Imaging in Hepatic Structure Segmentation

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the scarcity of reliable annotated datasets. To address this limitation, we propose 3D-LLDM, a label-guided 3D latent diffusion model that generates high-quality synthetic magnetic resonance (MR) volumes with corresponding anatomical segmentation masks. Our approach uses hepatobiliary phase MR images enhanced with the Gd-EOB-DTPA contrast agent to derive structural masks for the liver, portal vein, hepatic vein, and hepatocellular carcinoma, which then guide volumetric synthesis through a ControlNet-based architecture. Trained on 720 real clinical hepatobiliary phase MR scans from Samsung Medical Center, 3D-LLDM achieves a Fréchet Inception Distance (FID) of 28.31, improving over GANs by 70.9% and over state-of-the-art diffusion baselines by 26.7%. When used for data augmentation, the synthetic volumes improve hepatocellular carcinoma segmentation by up to 11.153% Dice score across five CNN architectures.

顶级标签: medical computer vision model training
详细标签: 3d latent diffusion synthetic medical imaging data augmentation hepatic segmentation controlnet 或 搜索:

3D-LLDM:用于提升肝脏结构分割中高分辨率合成磁共振成像质量的标签引导三维隐扩散模型 / 3D-LLDM: Label-Guided 3D Latent Diffusion Model for Improving High-Resolution Synthetic MR Imaging in Hepatic Structure Segmentation


1️⃣ 一句话总结

这项研究提出了一种名为3D-LLDM的新模型,它能根据肝脏等器官的解剖结构标签,自动生成高质量的合成三维磁共振图像,有效解决了医学图像分析中标注数据稀缺的问题,并能显著提升肝癌分割的准确性。

源自 arXiv: 2603.23845