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arXiv 提交日期: 2026-04-20
📄 Abstract - CAHAL: Clinically Applicable resolution enHAncement for Low-resolution MRI scans

Large-scale automated morphometric analysis of brain MRI is limited by the thick-slice, anisotropic acquisitions prevalent in routine clinical practice. Existing generative super-resolution (SR) methods produce visually compelling isotropic volumes but often introduce anatomical hallucinations, systematic volumetric overestimation, and structural distortions that compromise downstream quantitative analysis and diagnostic safety. To address this, we propose CAHAL (Clinically Applicable resolution enHAncement for Low-resolution MRI scans), a hallucination-robust, physics-informed resolution enhancement framework that operates directly in the patient's native acquisition space. CAHAL employs a deterministic bivariate Mixture of Experts (MoE) architecture routing each input through specialised residual 3D U-Net experts conditioned on both volumetric resolution and acquisition anisotropy, two independent descriptors of clinical MRI acquisition. Experts are optimised with a composite loss combining edge-penalised spatial reconstruction, Fourier-domain spectral coherence matching, and a segmentation-guided semantic consistency constraint. Training pairs are generated on-the-fly via physics-based degradation sampled from a large-scale real-world database, ensuring robust generalisation. Validated on T1-weighted and FLAIR sequences against generative baselines, CAHAL achieves state-of-the-art results, improving the best related methods in terms of accuracy and efficiency.

顶级标签: medical machine learning computer vision
详细标签: super-resolution mri hallucination-robust physics-informed mixture of experts 或 搜索:

CAHAL:面向低分辨率MRI扫描的临床适用性分辨率增强方法 / CAHAL: Clinically Applicable resolution enHAncement for Low-resolution MRI scans


1️⃣ 一句话总结

本文提出了一种名为CAHAL的MRI超分辨率方法,通过结合物理退化模拟、混合专家网络和多种约束损失,在提升低分辨率脑部MRI图像分辨率的同时,有效避免了传统生成式方法常见的解剖假象和体积测量偏差,确保了临床定量分析的准确性和安全性。

源自 arXiv: 2604.18781