基于堆叠集成方法对超声心动图进行鲁棒且可解释的二叶式主动脉瓣诊断 / Robust and Explainable Bicuspid Aortic Valve Diagnosis Using Stacked Ensembles on Echocardiography
1️⃣ 一句话总结
本文提出了一种可解释的人工智能模型,通过分析常规超声心动图视频片段,利用多模型堆叠集成技术,能够准确区分二叶式和三叶式主动脉瓣,同时提供可视化的诊断依据,有望在资源有限或非专家环境中帮助医生更早发现疾病。
Transthoracic echocardiography (TTE) is the first-line imaging modality for diagnosing bicuspid aortic valve (BAV), yet diagnostic performance varies with operator expertise and image quality. We developed an explainable AI model that distinguishes BAV from tricuspid aortic valves (TAV) using routinely acquired parasternal long-axis (PLAX) cine loops. A multi-backbone video ensemble was trained and evaluated using a leakage-aware, stratified outer cross-validation protocol on $N{=}90$ patient studies (48 BAV, 42 TAV). Across fixed outer splits and 10 random seeds, the calibrated stacked ensemble achieved an outer-CV F1-score of $0.907$ and recall of $0.877$. Frame-level Grad-CAM localized salient evidence to the aortic root and leaflet plane, while globally aggregated SHAP values quantified each video backbone's contribution to the stacked prediction, enabling transparent, case-level auditability. These findings indicate that PLAX-based video ensembles can support reliable BAV/TAV classification from routine echocardiographic cine loops and may facilitate earlier detection in non-specialist or resource-limited clinical settings.
基于堆叠集成方法对超声心动图进行鲁棒且可解释的二叶式主动脉瓣诊断 / Robust and Explainable Bicuspid Aortic Valve Diagnosis Using Stacked Ensembles on Echocardiography
本文提出了一种可解释的人工智能模型,通过分析常规超声心动图视频片段,利用多模型堆叠集成技术,能够准确区分二叶式和三叶式主动脉瓣,同时提供可视化的诊断依据,有望在资源有限或非专家环境中帮助医生更早发现疾病。
源自 arXiv: 2605.13730