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Abstract - BAC-JEPA: Label-Efficient Breast Arterial Calcification Segmentation via Synthetic Mammography-Guided Supervision
Breast arterial calcification (BAC) on screening mammograms is an emerging cardiovascular risk biomarker, but quantitative use requires reproducible segmentation and expert pixel-level labels are costly. We present BAC-JEPA, a label-efficient segmentation framework trained on procedurally generated arterial calcification inserted into real mammographic backgrounds with exact masks. Candidate backgrounds were selected from model-screened mammograms with low predicted BAC response; the generator samples arterial structure, disease burden, radiographic appearance, and hard-negative distractors including nonarterial calcifications and metallic objects. Synthetic masks are paired with mammography self-supervised Vision Transformer encoders and a high-resolution convolutional decoder to produce full-resolution segmentation maps. The study used 75,472 mammography studies from 34,956 patients for background selection and representation learning, trained on synthetic images from 10,000 backgrounds, selected checkpoints with 1,000 development backgrounds, and evaluated transfer on all 1,000 human-labeled BacSeg synthetic 2D mammograms. On held-out synthetic validation data, the larger backbone achieved IoU 0.5325 and Dice 0.6357. On BacSeg, image-level classification from segmentation probability maps reached AUROC 0.8719, with 0.8547 for the smaller backbone. Four-view inference required 110.68--213.63 ms on an RTX 5090 GPU, and severe-preset synthetic image generation averaged 2.7071 s per image on a multicore workstation. These results indicate that BAC-specific synthetic supervision can produce useful image-level transfer without human pixel-level training masks, while expert-reviewed real-mammogram segmentation remains necessary for clinical validation and calibration.
BAC-JEPA:通过合成乳腺X线引导监督实现标签高效的乳腺动脉钙化分割 /
BAC-JEPA: Label-Efficient Breast Arterial Calcification Segmentation via Synthetic Mammography-Guided Supervision
1️⃣ 一句话总结
本文提出一种名为BAC-JEPA的模型,通过在真实乳腺X线图像上合成模拟的动脉钙化病灶并自动生成精确标注,结合自监督视觉Transformer和卷积解码器,在不需要大量人工像素级标注的情况下,实现了对乳腺动脉钙化的高效分割和分类,其性能接近使用真实人工标注的方法,且推理速度极快。