基于深度学习的早产儿呼吸暂停检测 / Deep learning-based detection of cessation of breathing in pre-term infants
1️⃣ 一句话总结
本研究利用深度学习模型,通过分析早产儿在新生儿重症监护室中常规监测的心肺信号(如呼吸阻抗、心电图和血氧脉搏波),实现了对呼吸暂停事件的高准确率自动检测,发现信号类型对检测效果的影响远大于模型复杂度,其中呼吸阻抗信号表现最佳,多信号融合可进一步提升性能。
Apnoea of prematurity is characterised by recurrent episodes of cessation of breathing and remains difficult to detect reliably using routinely monitored physiological signals in the Neonatal Intensive Care Unit (NICU). Existing bedside monitors rely primarily on respiratory rate and oxygen saturation thresholds, often generating high false-positive alarm rates and missing short or irregular events. Improving automated detection using routinely acquired clinical signals could enhance identification of clinically meaningful events without additional sensing hardware. We evaluated deep learning-based detection of apnoea-related Cessation Of BrEathing (COBE) events using impedance pneumography (IP), electrocardiography (ECG), and photoplethysmography (PPG) signals from approximately 430 hours of NICU recordings collected from 24 pre-term infants. Three independent reviewers annotated COBE events, producing a dataset of 346 COBE and 608 non-COBE events. We compared a shallow convolutional neural network (CNN), residual networks (ResNets), and a ConvNeXt architecture using an independent held-out test set. Across all architectures, detection performance was influenced more strongly by signal modality than by architectural complexity. Unimodal IP-based models achieved balanced accuracies of 86.8-88.0%, outperforming ECG-derived (62.6-69.7%) and PPG-derived (65.1-66.4%) respiratory surrogates. Multimodal fusion yielded modest improvements over IP alone. The best-performing model, a ConvNeXt architecture combining IP and PPG inputs, achieved 88.7% balanced accuracy and an F1 score of 0.75 on the independent test set. These findings demonstrate that deep learning models applied to routinely monitored NICU signals can reliably detect COBE events and highlight the importance of signal modality in data-constrained neonatal monitoring settings.
基于深度学习的早产儿呼吸暂停检测 / Deep learning-based detection of cessation of breathing in pre-term infants
本研究利用深度学习模型,通过分析早产儿在新生儿重症监护室中常规监测的心肺信号(如呼吸阻抗、心电图和血氧脉搏波),实现了对呼吸暂停事件的高准确率自动检测,发现信号类型对检测效果的影响远大于模型复杂度,其中呼吸阻抗信号表现最佳,多信号融合可进一步提升性能。
源自 arXiv: 2606.23213