基于CTPA和病历的肺栓塞风险分层:血管图并非万能 / Pulmonary Embolism Risk Stratification from CTPA and Medical Records: Vascular Graphs Are Not All You Need
1️⃣ 一句话总结
该研究通过对比多种模型发现,在进行肺栓塞风险分层时,病历和心脏生物标志物等全局特征比复杂的血管图像信息更有效,甚至血管结构图神经网络也无法超越简单的表格模型,提示血管图形可能并不包含对风险分层有用的判别信息。
Risk stratification for pulmonary embolism (PE) is critical for clinical decision-making. Stratification guidelines are based on patient medical records, parameters measured from computed tomography pulmonary angiography (CTPA), and blood tests. However, blood tests are often missing in routine practice. This work studies whether state-of-the-art models can accurately classify risk stratification from only medical records and biomarkers extracted from CTPA images. We benchmark different approaches to combine medical records and cardiac biomarkers with rich pulmonary vascular information; we add vascular biomarkers to tabular models and apply graph neural networks (GNNs) on the vascular tree's intrinsic graph representation. We use a private dataset (n=353) with uniquely complete data for PE risk stratification. Our results show that, among global features, medical records and cardiac biomarkers are the most significant predictors, while vascular biomarkers do not further improve stratification. Even more surprising, even GNNs on vascular graphs fail to outperform strong tabular baseline on global features. We consider hypotheses, on both models and data, that could explain this suboptimal performance. Our investigation suggests that, counter-intuitively, vascular graphs might hold no discriminative information for PE risk stratification. Code is available from this https URL.
基于CTPA和病历的肺栓塞风险分层:血管图并非万能 / Pulmonary Embolism Risk Stratification from CTPA and Medical Records: Vascular Graphs Are Not All You Need
该研究通过对比多种模型发现,在进行肺栓塞风险分层时,病历和心脏生物标志物等全局特征比复杂的血管图像信息更有效,甚至血管结构图神经网络也无法超越简单的表格模型,提示血管图形可能并不包含对风险分层有用的判别信息。
源自 arXiv: 2606.25956