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This paper introduces a quantum-inspired computational framework for harmonic decision-making in music. The proposed approach formulates harmonization as an optimization problem within a structured combinatorial space, where multiple candidate chord sequences are evaluated under interacting musical constraints. The model combines an interference-based harmonization stage with a classical optimization procedure grounded in tonal harmony. The quantum-inspired component enables the parallel consideration of multiple harmonic alternatives, while the classical stage refines the resulting sequences to ensure structural coherence and stylistic plausibility. The framework is evaluated on selected musical examples, including Autumn Leaves and It's a Long Way to Tipperary. Quantitative analysis shows that the optimization stage significantly reduces chord density, increases harmonic stability, and improves functional organization. At the same time, expert evaluation highlights the importance of stylistic context, demonstrating that increased harmonic complexity is not always perceived as more natural. The results suggest that harmonic generation can be interpreted as a structured decision-making process in a constrained search space. The proposed approach provides a computational model that integrates domain-specific knowledge with an interference-based search mechanism. Although preliminary, this work indicates that quantum-inspired methods may offer a useful framework for modeling complex decision processes in creative domains such as music. The proposed framework contributes to ongoing research on quantum-inspired models of cognition and decision-making in complex biological and creative systems.