基于CT-CLIP表征的多模态肺癌生存预测 / CT-CLIP Representations for Multimodal Lung Cancer Survival Prediction
1️⃣ 一句话总结
本研究评估了领域专用基础模型CT-CLIP在肺癌生存预测中的应用,发现使用冻结的CT-CLIP模型结合轻量可训练生存预测头,即使在小规模数据集上也能超越传统临床模型,有效区分高危和低危患者。
Accurate prognosis prediction is important for treatment planning in lung cancer, but deep learning-driven survival modelling is often limited by the scarcity of curated imaging cohorts with reliable outcome data. This study evaluates whether representations from a domain-specific foundation model can be used for multimodal survival prediction in data-constrained clinical settings. We assess the foundation model CT-CLIP as a feature extractor for pretreatment computed tomography images and clinical variables from 242 diagnosed lung cancer patients. The evaluation includes adaptation strategies based on frozen encoders, full fine-tuning, and low-rank adaptation, together with modality ablations and comparisons with clinical and multimodal baselines. The results show that a frozen CT-CLIP model combined with a trainable lightweight survival head outperforms the clinical baseline and achieves comparable or improved performance relative to other multimodal approaches, and separates patients into clinically meaningful high- and low-risk groups.
基于CT-CLIP表征的多模态肺癌生存预测 / CT-CLIP Representations for Multimodal Lung Cancer Survival Prediction
本研究评估了领域专用基础模型CT-CLIP在肺癌生存预测中的应用,发现使用冻结的CT-CLIP模型结合轻量可训练生存预测头,即使在小规模数据集上也能超越传统临床模型,有效区分高危和低危患者。
源自 arXiv: 2607.08503